Bookmark and Share

Penicillin is a family of antibiotics that inhibit the systhesis of the bacteral cell wall don't just slow their growth, they kill bacteria. Penicillins are considered one of the most safe antibiotics to take during pregnancy. They are used to treat common pneumonia and other infections caused by streptococci, skin infections, syphilis (first line treatment Penicillin G), meningitis, listeria, and actinomyces. Allergy is the most common adverse effect including urticaria, rash, and in some cases presents a more severe reactions known as anaphylactic shock, delayed rash 1-2 weeks later, and/or superinfection due to bacterial (clostridium difficile) overgrowth in the GI (gastrointestinal system) causing enterocolitis mostly in long term therapy where the healthy intestinal flora is replenished (and here comes the importance of probiotics). Since penicillin was introduced during world war II, penicillin has provided effective treatment for a multitude of infections. Over time, many bacteria have designed ways to defeat penicillin.
This description is a member contribution, please read our disclaimer regarding user-generated content.

Pages : 1 2

New message

Questions, experiences and reviews (48)

Message Written by
How long does it take for penicillin to get out of your system?
I am in the midst of an allergic reaction to penicillin, and I would like to know when this will go away. I took 1,000 milligrams a day for four days, and noticed the allergic reaction yesterday. I have not taken any penicillin since Thursday night, but I still have the hives and itching. I've been taking Benadryl like crazy. When will the penicillin get out of my system and the reaction pass?
miss elaineous
12/15/07
Reply
  Penicillin has a pretty short half life (the time it takes for the amount in your body to be reduced by half) of about 1 hour. After 5 half-lives, ~95 percent of the drug should be eliminated by your kidneys. Some forms of penicillin such as amoxicillin may remain slightly longer in the body until eliminated.

Basically after a day if not re-dosed it should be out of your system. However the allergic reaction may last longer due to the histamine which still remains in the skin released by your white blood cells which view penicillin as a foreign substance. That's why the hives and itching can continue even though you've stopped the penicillin.

Keep taking the Benadryl™ and if you are still bothered by Monday your doctor could prescribe an oral steroid. Topical hydrocortisone cream can be used on more severely affected areas to help relieve some of the itching.
naugahide
12/15/07
How long does it take for Penicillin V to work?
Okay, so I've had a very low grade fever (from 99.5-100.3) on and off for going on 3 weeks now. Since I don't have medical insurance, I wasn't able to go to a doctor as I'm quite broke. My symptoms finally got bad enough for me to find a doctor, and what went from an upper respiratory infection has now become tonsillitis.

The doctor has perscribed me 500mg of penicillin to be taken 4 times a day. While my fever still comes and goes, I'm on my third day of taking the penicillin, and I still don't feel any better. How long does it take the penicillin to take effect? Could the infection maybe be viral, which is why the penicillin doesnt seem to be taking effect yet?
Davey
09/16/09
Reply
  Your infection might be bacterial but resistant to penicillin or it might just be taking some time to get better. It might be viral...many infections are. Be sure to take the penicillin on an empty stomach or it wont be well absorbed.
birdie
09/16/09
Why would a strain of Staphylococcus aureus become resistant to penicillin?
Assume that you are a microbiologist who has been doing research on a penicillin-sensitive strain of Staphylococcus aureus for many months. One day you discover that the organism is now resistant to penicillin. You know that it has not come in contact with any other species of bacteria, nor has it come in contact with the DNA from any other species of bacteria. What are two possible explanations for its sudden change from penicillin susceptibility to penicillin resistance?
mikeyblueyes
01/31/09
Reply
  Genetic mutation.
All it takes is one little bacterium with a gentic mutation that makes it immune to your penecillin. If it manages to survive and replicate, it will create a whole bunch of little baby mutuants, that will live long and prosper without fear of your deadly penecillin.

A second way... hmm... not sure.
Danielle D
01/31/09
How long after finish my Penicillin can I drink?
I had some oral surgery last week and was on Penicillin for 7 days... I took the last dose about 12hrs ago. How long should one wait before drinking alcohol after finishing his penicillin?
Miguel Saucedo
04/29/11
Reply
azithromycin or penicillin for tooth infection?
Back in june I had an infected wisdom tooth, which i was given penicillin for until my dental insurance kicks in at the end of october. well, last week i was at the doctors office for an ear infection and was giving azithromycin for it. Yesterday my tooth infection returned (I know my ear isnt related to my tooth..different sides and i saw the dr), so my dentist prescribed the penicillin again and some dolobid for the pain. So my 2 questions are:

Can i take the penicillin while on the azithromycin, or should i wait until i finish that up on saturday and maybe start the penicillin monday or tuesday?

And also, how is dolobid? I never took it before and I am worried it's going to keep me up all night or make me sick, although most things make me sleepy.

Thanks to anyone who can help!
Kristen
09/10/09
Reply
  These are not questions you should be asking here. Call your dentist and tell him you are on arithromycin and why and ask him what to do next. He may want to coordinate something with your other doctor. This is definitely the time to ask a professional, and his advice and guidance should be free when you call. By the way, you should have told the dentist office when you went in tthat you were already on another med.
Go make that phone call!
Good luck! :)
Cookie Preston
09/10/09
Could I do something about the ER doctor?
I took my 5 year old son to emergency room yesterday morning. He was running a fever and throwing up. He has asthma and has an allergy of trimox which is a form of penicillin, his dad is allergic to penicillin and so is his older sister. I told them this and they put the orange allergy band on him with PCN which of course lets nurses and doctors know he is allergic to penicillin. Well, he has Strep throat and the er doctor prescribed him penicillin. The pharmacy where I get prescriptions filled had a red flag when they started to fill his prescription. Needless to say, they did not fill it and I called his doctor to have them phone him in another prescription for an antibiotic other than penicillin. Do you think I could do anything about this? If the pharmacy would not have caught this, My son could have had severe reactions to this medicine.
amyj19692006
03/10/09
Reply
  This is the problem with emergency room doctors, they are over worked and get little sleep. And yet this is the way America trains her doctors. No forget about it, you did the right thing, and so did the pharmacy. Good that they had a flag on his records. I read an article in my doctors office yesterday that when you have a patient in the hospital or a relative, you should always have someone with that patient, and they should always ask what the medications are he or she is receiving. So many times in hospitals now, patients are given the wrong medications. Google Denis Quaid + too much blood thinner.
He appeared before Congress, to try and prevent what happened to his new born twins from happening to any other patients. They almost died from an overdose of blood thinner. And he was concerned when he found out this happens every day in hospitals in america.
He will be on the Oprah show today, you should watch it, gives all sorts of information about how doctors and hospitals make mistakes and how we as patients can insure that we and our relatives get good care.
Anne2
03/10/09
Penicillin?
If Im taking 4 tablets a day of penicillin for a UTI, how soon should this horrible burning sensation go away? I just started my penicillin tonight (2 tablets).

Is this buring sensation normal? How about a desire to urinate but only having 5ml come out? What about having less control of my bladder (urine just flying out)?
alf314888
02/23/07
Reply
  In a couple of days the burning and frequency should have abated. You will probably start to feel some relief by tomorrow.
Penicillin is a broad spectrum antibiotic which works quickly. In the meantime, try to avoid any high acid intake (Citrus, tomato, pepper and even aspirin).

I hope you feel better soon. Don't forget to finish your prescription completely.
Jack
02/23/07
What does Penicillin do for a toothache?
Alright, so I had a toothache for about 3 days. I went to the dentist yesterday and he prescribed Penicillin to me. I wanted to know what will the Penicillin do for my toothache?
mmarzan
10/15/11
Reply
  Julia is right, this will not address the noiceptors involved in pain.
frank
10/15/11
Hey, any pharmacists out there?
I have strep throat and am taking penicillin (2-3x/day) But I also have a UTI. Can I take penicillin and Sulfatrim together?
actually both have been perscribed to me...Penicillin today and Sulfatrim a couple of weeks ago...have re-occuring UTI's and my doc said to use the Sulfatrim when needed. But when picking meds for my strp throat I forgot to ask the pharmacist.
daisygirl
09/25/06
Reply
  yes you can use both......there are alternative antibiotics that will likely resolve both
jloertscher
09/26/06
why is this penicillin for animal use only?
http://www.amazon.com/gp/product/B0002YF9V4 i looked at that penicillin its made by durvet its penicillin G procaine and ive seen online that it has human used (stds, utis, other various infections) but the bottle i linked says "not for human use" is it a different kind or something? is it dangerous to use in humans or just not effective?
im not planing to use it i get its not for human use i allready stated that, my question was "why its not for human use?"
Samuel K
07/23/11
Reply
How do you get penicillin into your body?
Just out of curiosity, how does a person take in penicillin? I mean is it a tablet or a syrup or an injection?
cat_lover
10/24/06
Reply
  All 3.
bmac
10/24/06
can you build up a tolerance for penicillin?
Specifically, Penlac?( A penicillin laquer for the nails)
antonio andolini
05/24/08
Reply
  You dont build the tolerance, you bacteria does. And anyones bacteria can build up a tolerance for any antibiotic.
This is why when prescribed antibiotics, the person must finish all of them even if symptoms have disappeared. This is also why they should only take them if they need them. Some doctors prescribe them for viral infections just to make the patient happy---not good. And this is also why doctors shouldn't keep prescribing the same antibiotic to you.
aljea
05/24/08
penicillin vk?
what kind of fever reducer medication can be used along with the penicillin vk 250mg/5ml soln 200ml for a 7 year old?
Tracy
01/09/07
Reply
  Motrin or Tylenol but do them separate times. Like an 1 or 1/2 hour in between. If there is ear ache than I would use Motrin because it takes the swelling down.
Marina
01/09/07
Why won't my tonsillitis go away? It's been over a month and a week and i still have it..help!?
Ive had tonsillitus about 7 or 8 times before but have never gone to the doctors for antibiotics because it usually gets better after a week. On Feb 20th i got it again and deided to go to my GP. The doctor gave me 250 mg of penicillin 4 times a day for 7 days and took a throat swab. The penicillin seemed to work and by the end of the 7 days i felt OK but then a couple of dayslater it came back so i went back to the GP who then gave me a futher 4 days of penicillin and said the swab came back with strep throat which was sensitive to penicillin. Then after these four days i felt ok again but got ill a couple of days later and went back to the GP who then gave me 250mg of penicillin to be taken 8 times a day for 7 days. The same thing happened..it made me better then a few days after i finnished the course i got ill again. I went back to my Gp and am now on erythromycin stearate but nothing seems to be happening. Why wont it go away?If i hadnt gone to the GP would it be better by now?
.
03/30/08
Reply
  It wouldn't be better if you hadn't gone to the GP.
You may have a weakened immune system which is why you haven't stayed better.

I agree that you ought to go to an ENT MD. However, if the ENT tell you to get tonsils out...go for 2nd opinion.

To boost immune system immediately:

Vit. C 2000mg. every 2 hours
Suck on Zinc lozenges.
Suck on cough drops with eucalyptus.
Zinc 50 mg.
Echineacea
Goldenseal root (only 5 days in a row)
Astragalus

Hope you feel better soon.
knicname
03/30/08
I am SEVERELY allergic to penicillin. My doctor prescribed me cefdinir for a sinus infection should i take it?
im so afraid to take it. i had anifilatic shock when i toke penicillin as a baby..PLEASE HELP!!!!
Alyssa
02/20/11
Reply
Penicillin V reaction?
About 2 months ago I took penicillin V tablets. I took to tablets that day because your suppose to take 1 every six hours. after the first day of taking it I noticed small bumps on my arms and my feet were itching really bad. I didn't take it anymore after that. Then a couple of weeks later the skin on my hands and feet started to peel and i got a rash on my left foot. Is this a sign that I had a allergic reaction to it? and has anyone esle experienced this after taking Penicillin?
Lamarr
08/14/07
Reply
  my wife had that problem

it's some kind of allergic reaction

just tell the doctor that you can't take that and they usually will have a back up drug instead
You may be right
08/14/07
can Penicillin (VK penicillin v potassium) or Ibuprofen make you gain weight taken alone or together?
i have a reallyy bad infection in my gums caused by my upper wisdom teeth coming in
jessikalauren8807
04/01/10
Reply
  Uh no. It is just an antibiotic and over the counter pain med.
S P
04/01/10
Im taking Birth Control and Penicillin, Why am I bleeding?
I have been taking Birth Control pills for 3 months now. This past week I took penicillin because I got sick from strep throat. I take the BC pills in the morning, then I take penicillin 2 hours after. Now I realize that I'm bleeding and its not the time of my period.. I just want to know if anyone can explain what might happen or if I had a miscarriage?
sillygoose
09/23/10
Reply
Why was I prescribed Septra for strep throat?
As I understand it, Septra is primarily used for urinary tract infections and (rarely) for strep throat when the patient has a penicillin allergy. I specifically told my doctor today that I am not allergic to penicillin and that I was prescribed penicillin the last time I had strep throat (~ 1 year ago).

Is there something I'm missing?
1O Cαиe
01/19/10
Reply
  You're right, it is usually prescribed for UTI's, however this article lists other infections it can be used for. My daughter was prescribed a sulpha drug one time for an infection she got after knee surgery. Turns out she is allergic to sulpha drugs. When I took her to our family Dr he kinds just shook his head about the sulpha prescribed.

http://www.drugs.com/septra.html
mstess
01/19/10
penicillin?
i had strept throat about a month ago and i was prescribed penicillin. i took it until the symptoms went away and still have about half of the bottle. now i am starting to get an irritated throat and am wondering if I should finish the bottle??? it might be a throat thing or it also might just be a cold since it is going around to everyone right now. will penicillin cure a cold also??
i know i am supposed to take the whole thing, but i moved and lost the bottle in the move!
wakedreamin4
12/24/07
Reply
  You have to start and finish all your medication, it's very important, but in this case I recomend to you, "GO AND CHECK WITH UR DOCTOR"
♥ Diana ♥ ...On Vacation
12/24/07
Is Penicillin V Potassium good to treat urinary tract infections?
Yesterday I had my wisdom teeth removed and was prescribed a pain killer, penicillin V Potassium, and another pills. But the night before the surgery I developed a urinary tract infection. I had one just 2 months ago and took amoxicillin but took half the bottle because the pills were too big. Will the penicillin I am taking for my tooth get rid of my uti? The uti pain is horribly bad, worse than my first one. Thank you for your answers!! :)
Kate
01/08/10
Reply
  Yes, its a gram positive & Negative Antibiotic. UTI's are Gram Positive. As long as you take it LONG enough it should also help that too. You may notice elevated body temps.. a little fever..but just watch yourself. Azo helps too.. it coats the UT so the bacteria cant hold onto it...kinda like putting super slick stuff on a slide.. It also makes your Pee Orange but thats ok. You can also get the Azo that has cranberry extract which helps your UT heal. The Bacteria cause alot of inflamation down there. Take some Anti-inflamitories.. Aleve, Ibuprofen and that will help but its not for the pain.. You said you had a pain killer too.. probably 10/325 Hydro codone and or Perco-Cet...those will help with the pain. It would be better if you had Amoxcillin, its more specific along with Pen G. But.. since this is all you have.. it may work. If its not better in 2 days.. GO TO THE DOCTOR.

Edit to Add - TAKE ALL YOUR MEDS, NOT HALF! Otherwise it WILL come back. Even if you feel FINE!

Hope you feel better
TheSwabbie
01/08/10
how do I administer penicillin to my dog for an eye infection?
My weenie dog has goop in his eyes all day and night. I don't know whether to give the penicillin in his muscle, orally or just under the skin. So, I've tried orally and it's not working. What should I do?
Georgia O
05/25/08
Reply
  I think penicillin is mostly used for bacterial infections. However I think your doggie may need an eye ointment, something that can be drooped into the eye. He may have something in his eye than you cannot see, that has irritated him, and now there is a discharge. If you can't get to the vet, maybe go to your local feed store and see what they suggest. Feed stores usually have med's for dogs.
jealbaroma
05/25/08
STREP THROAT. i heard you shouldnt eat when taking penicillin... ?
one of the questions here asked how long before you can eat non astronaut food basically. now either they meant because of the strep throat discomfort or because penicillin can only work on an empty stomach?

sorry for sounding stupid but this is my first time having strep throat.

i think its gotten a little better. this is day 3 of taking penicillin (2 pills, 3 times a day, 3 days, then 2 pills a day, twice for 7 days)

it still hurts alot to swallow when am i gonna see results? (ibuprofen not helping much)
Golden Femurr
02/15/08
Reply
  When you are sick is when you need the most nutritious food, so you definitely eat when taking penicillin. I know you probably don't have much appetite, and it probably still hurts to swallow, but you need to try all you can to eat real, nutritious food. Warm soup is good and so it hot tea; both are soothing. But you need real, solid food as well. The penicillin treats the infection, so by eliminating the infection, you will eventually begin to feel better, but in the meantime, you also need symptom relief in order to feel better now. Someone mentioned Tylenol or ibuprofen. Use either/or, but not both. Warm fluids are soothing, as we said, rest if helpful and drink a lot of water. OJ is good too. I've known people who put a sprinkle of cinnamon on top of OJ and warm it up in the microwave, just because warm fluids are soothing....I don't know if it's good, but you might want to try it--you might like it..Hope you feel better soon.
cheruvima
02/15/08
can u take cefuroxime axetil if allergic to penicillin?
i have a tooth ache and i believe it is infected can i use this medication for it even though im allergic to penicillin
Scotty Douglas
03/17/11
Reply
Could Penicillin Be Causing These Symptoms?
I was put on Penicillin (2 tabs 3x a day) on Friday. For Strep Throat.

I find I am dizzy after taking it, and I get hot sometimes right after taking it.

Also I have developed a cough with some phlegm... what the hell is going on! I thought I was supposed to get better!!
Confused girl
01/18/11
Reply
Can I take Penicillin VK for an ear infection?
I havent been to the doctor. My ears feel really clogged and it hurts, especially at night. Everything sound muffled. My moms dentist prescribed her penicillin vk 250 mg and she hasnt taken them. Will that help my ear infection? Will it harm me if i take it anyway just to see if it will help?
Casey
12/02/11
Reply
Penicillin VK?
Can Penicillin VK get you high? If so how many do you need to take to get high? How many does it take to overdose and what are the effects of the high you get from Penicillin VK if there is any from it?
REMO
05/27/07
Reply
  No you can't get high from it. This is an antibiotic. Used to treat infections.
angel
05/27/07
Taking penicillin v potassium every day,what are the side effects,if any?
I have Lymphedema,an have been in hospital may,june an july,5days each month.It keeps on coming back an that is why the doctors put me on penicillin to try to keep the cellisitis from coming back.Any ideas,help
marierod
07/31/09
Reply
  penicillin every day?. you'll wipe out your good (natural) flora of your digestive system leading to numerous stomach and intestinal problems. And, when you do get infected with something, penicillin and P-based AB wont be much effective.
delco714
07/31/09
How many times a day should I take penicillin?
I had two wisdom teeth removed and my dentist wants me to take a pill of penicillin vk 4 times a day for 7 days. The bottle however says take one pill every 6 hours. Do I take 3 pills each day? Help!
jake s
04/25/10
Reply
  Ask the druggist. Usually you divide the day up without making yourself wake up in the middle of the night to take a pill. Start the penicillin (never skip one) and call the dentist and/or the druggist to get this clarified. Maybe you have a stronger pill than the dentist thought you would be getting and three a day are enough. Don't guess because you need enough penicillin to be sure you don't get an infection and not so much you have problems.
keiko
04/25/10
Should I go to the Hospital?
I was taking Penicillin for Strep Throat - 7 days ago, I have 10 days of Penicillin (2 Tabs, 3 x a day) I'm saying this because I dont know if taking the Penicillin is related to my symptoms or not.

5 days ago I started getting "hot" and feeling like I was hot. 3 days ago, I had chills, pretty bad and then got really hot all in the same night. I continue to feel like it's las Vegas outside and I live in snowy Alberta.

I also have some soreness/stiffness in my lower back. I am sneezing and I feel extremely irritable.

Do I need to go to the hospital? The Doctors isn't open until Tuesday, and Walk in Clinics are open tomorrow but I honestly dont feel I can wait.
Confused girl
01/22/11
Reply
  if you really feel like it can not wait then i would go if you are that concerned and feeling that bad.
peace and love
01/23/11

Pages : 1 2
Videos

Consumer feedback Disclaimer
Status updates

ashbashn: Doc: r u allergic to anything? Me: yes penicillin, doc:take these antibiotics there only penicillin based you'll be fine me: ur kiddin rite!
thisworldis1: Penicillin 2/20
Jdotdor_rpt: This penicillin better work
streetfame1: @KevinHart4real there's penicillin for that
AlicynWondrland: @Doodlewee ha ha, are you making penicillin or something?
kelseaamber: @TheFredFamous oi cheeky! im allergic to penicillin so have to take other ones! :P x